BDBM149354 US8962859, 9A

SMILES NC1=N[C@]2(c3cc(-c4cccnc4F)ccc3Oc3c(F)cc(N4CCOCC4)cc32)c2nccn21

InChI Key InChIKey=OLMKWMUFWPWVRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149354   

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 149354BDBM149354(US8962859, 9A)
Affinity DataIC50: 189nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent