BDBM150123 US8975417, 191
SMILES CCn1nc(C)c2[C@H](N(C(=O)c12)c1cc(C)c2nnc(C)n2c1)c1ccc(F)cc1F
InChI Key InChIKey=PXLJQXYHONWMKB-LJQANCHMSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 150123
Affinity DataIC50: 31nMpH: 7.5 T: 30°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMpH: 7.5 T: 30°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 7.5 T: 30°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 30°CAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair