BDBM150687 US8987254, 2

SMILES NC1=N[C@@]2(c3cccc(NC(=O)c4cnc(CO)cn4)c3)CN(c3ncc(F)cn3)C[C@H]2CS1

InChI Key InChIKey=DIMKSDGXKNXQSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150687   

TargetBeta-secretase 1(Human)
Eli Lilly

US Patent
LigandChemical structure of BindingDB Monomer ID 150687BDBM150687(US8987254, 2)
Affinity DataIC50: 0.482nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent