BDBM151044 US8987268, 63

SMILES CNC(=O)c1ccc(cn1)-c1cc2c(N[C@@H]3C[C@@H]4CN(C[C@@H]4[C@H]3C)C(=O)C(C)(C)O)c(cnn2c1)C(N)=O

InChI Key InChIKey=DZRNUAOUPKHAOG-ROZLJVEFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151044   

TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151044(US8987268, 63)
Affinity DataIC50:  0.400nMpH: 7.4 T: 25°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151044(US8987268, 63)
Affinity DataIC50:  0.700nMpH: 7.4 T: 25°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
In DepthDetails US Patent