BDBM151054 US8987268, 126

SMILES CC[C@@H]1CN(CC[C@H]1Nc1c(cnn2cc(cc12)-c1cnn(CCC#N)c1)C(N)=O)S(C)(=O)=O

InChI Key InChIKey=YDBAZCZNEPOFIH-DNVCBOLYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151054   

TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151054(US8987268, 126)
Affinity DataIC50:  1nMpH: 7.4 T: 25°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151054(US8987268, 126)
Affinity DataIC50:  1.5nMpH: 7.4 T: 25°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
In DepthDetails US Patent