BDBM151075 US8987268, 292

SMILES CC[C@H]1CN(C[C@H]1Nc1c(cnn2cc(cc12)-c1cc(C)no1)C(N)=O)C(=O)OC(C)(C)C

InChI Key InChIKey=MJHBBCZEVXDESQ-WMLDXEAASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151075   

TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151075(US8987268, 292)
Affinity DataIC50:  0.700nMpH: 7.4 T: 25°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151075(US8987268, 292)
Affinity DataIC50:  0.5nMpH: 7.4 T: 25°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent