BDBM151496 US8987314, B307

SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccccc1F)S(=O)(=O)CCC(F)(F)F

InChI Key InChIKey=FQAITXRGECDYOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151496   

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151496(US8987314, B307)
Affinity DataIC50:  1.5nMpH: 8.0 T: 25°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151496(US8987314, B307)
Affinity DataIC50:  3nMpH: 8.0 T: 25°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent