BDBM15158 1-[1-({4-[6-(butan-2-yl)-5-oxo-3-phenyl-4,5-dihydropyrazin-2-yl]phenyl}methyl)piperidin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one::pyrazinone 13e

SMILES CCC(C)c1nc(-c2ccc(CN3CCC(CC3)n3c4ccccc4[nH]c3=O)cc2)c([nH]c1=O)-c1ccccc1

InChI Key InChIKey=ILSSGVAAXSWLME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15158   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM15158(1-[1-({4-[6-(butan-2-yl)-5-oxo-3-phenyl-4,5-dihydr...)
Affinity DataIC50:  1.70E+4nMpH: 7.5 T: 22°CAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRAC-gamma serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM15158(1-[1-({4-[6-(butan-2-yl)-5-oxo-3-phenyl-4,5-dihydr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM15158(1-[1-({4-[6-(butan-2-yl)-5-oxo-3-phenyl-4,5-dihydr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed