BDBM151971 US8987457, 165
SMILES COc1cc(F)c(c(F)c1)-c1nc(ccc1F)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)[C@H](OCCC#N)[C@H](N)C1
InChI Key InChIKey=YYOYATJEOKTTDV-WOHUVRFHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 151971
Affinity DataIC50: 0.950nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair