BDBM152656 4-(1,3-Dioxoisoindolin-2-yl)-N-(naphthalen-1-yl)benzenesulphonamide (19)

SMILES O=C1N(C(=O)c2ccccc12)c1ccc(cc1)S(=O)(=O)Nc1cccc2ccccc12

InChI Key InChIKey=ZREPMXUPUFTDRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152656   

TargetGenome polyprotein(DENV-2)
Queensland University of Technology

Curated by ChEMBL
LigandPNGBDBM152656(4-(1,3-Dioxoisoindolin-2-yl)-N-(naphthalen-1-yl)be...)
Affinity DataIC50:  1.22E+5nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease using Bz-Nle-Lys-Arg-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

LigandPNGBDBM152656(4-(1,3-Dioxoisoindolin-2-yl)-N-(naphthalen-1-yl)be...)
Affinity DataIC50:  1.22E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed