BDBM152735 11-bromo-5-{4-[4-(trifluoromethoxy)phenyl]piperazine-1-carbonyl}-8,10-dithia-3,4-diazatricyclo[7.3.0.0 ,⁶]dodeca-1(9),2,5,11-tetraene (7e)

SMILES O=C(c1[nH]nc2c1CSc1sc(Br)cc1-2)N1CCN(c2ccc(OC(F)(F)F)cc2)CC1

InChI Key InChIKey=APVBGTLCSZVRES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152735   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

LigandChemical structure of BindingDB Monomer ID 152735BDBM152735(11-bromo-5-{4-[4-(trifluoromethoxy)phenyl]piperazi...)
Affinity DataIC50: 8.60E+4nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed