BDBM152865 US8993586, 43

SMILES CC1=CC(C(=O)N2CCC3(CC2)Cc2cn(C(C)C)nc2C(=O)N3)=CC2C(C)=NNC12

InChI Key InChIKey=MBLCKXOZBFOELZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152865   

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 152865BDBM152865(US8993586, 43)
Affinity DataIC50: 11nMAssay Description:Preparation of rhACC2. Human ACC2 inhibition was measured using purified recombinant human ACC2 (hrACC2). Briefly, a full length Cytomax clone of ACC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 152865BDBM152865(US8993586, 43)
Affinity DataIC50: 29nMpH: 7.5Assay Description:Preparation of rhACC1. Two liters of SF9 cells, infected with recombinant baculovirus containing full length human ACC1 cDNA, were suspended in ice-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent