BDBM152880 US8993586, 60

SMILES CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]nc(C#N)c4c3)CC1)C2

InChI Key InChIKey=MLFHKQCEQNQXDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152880   

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 152880BDBM152880(US8993586, 60)
Affinity DataIC50: 14nMAssay Description:Preparation of rhACC2. Human ACC2 inhibition was measured using purified recombinant human ACC2 (hrACC2). Briefly, a full length Cytomax clone of ACC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 152880BDBM152880(US8993586, 60)
Affinity DataIC50: 43nMpH: 7.5Assay Description:Preparation of rhACC1. Two liters of SF9 cells, infected with recombinant baculovirus containing full length human ACC1 cDNA, were suspended in ice-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent