BDBM153704 2-(4-((3,4-Dihydroisoquinolin-2(1H)-yl)methyl)phenyl)-3-phenyl-1,6-naphthyridin-5(6H)-one (7c)
SMILES O=c1[nH]ccc2nc(-c3ccc(CN4CCc5ccccc5C4)cc3)c(cc12)-c1ccccc1
InChI Key InChIKey=XTVLFWXXYOVKNH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 153704
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund
Technische Universit??????T Dortmund
Affinity DataKd: 6.00E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund
Technische Universit??????T Dortmund
Affinity DataIC50: 900nMAssay Description:IC50 determinations for activated Akt1 were measured with the KinEASE assay (Cisbio) according to the manufacturers instructions. The kinases A...More data for this Ligand-Target Pair