BDBM153706 2-(4-((4-(4-Methoxyphenyl)piperazin-1-yl)methyl)phenyl)-3-phenyl-1,6-naphthyridin-5(6H)-one (7e)
SMILES COc1ccc(cc1)N1CCN(Cc2ccc(cc2)-c2nc3cc[nH]c(=O)c3cc2-c2ccccc2)CC1
InChI Key InChIKey=NKXWBWPQHSXKTE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 153706
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund
Technische Universit??????T Dortmund
Affinity DataKd: 7.20E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund
Technische Universit??????T Dortmund
Affinity DataIC50: 1.40E+3nMAssay Description:IC50 determinations for activated Akt1 were measured with the KinEASE assay (Cisbio) according to the manufacturers instructions. The kinases A...More data for this Ligand-Target Pair