BDBM153710 7-(4-methylphenyl)-5-phenyl-N-(pyridin-3-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (8b)
SMILES Cc1ccc(cc1)-n1cc(-c2ccccc2)c2c(NCc3cccnc3)ncnc12
InChI Key InChIKey=SDPWVUARKSHHGK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 153710
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund
Technische Universit??????T Dortmund
Affinity DataKd: 7.80E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund
Technische Universit??????T Dortmund
Affinity DataIC50: 1.60E+5nMAssay Description:IC50 determinations for activated Akt1 were measured with the KinEASE assay (Cisbio) according to the manufacturers instructions. The kinases A...More data for this Ligand-Target Pair