BDBM153712 5,7-diphenyl-N-(thiophen-2-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (8d)

SMILES C(Nc1ncnc2n(cc(-c3ccccc3)c12)-c1ccccc1)c1cccs1

InChI Key InChIKey=SROXNAMMCJVCBO-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153712   

TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund

LigandPNGBDBM153712(5,7-diphenyl-N-(thiophen-2-ylmethyl)-7H-pyrrolo[2,...)
Affinity DataKd:  2.20E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund

LigandPNGBDBM153712(5,7-diphenyl-N-(thiophen-2-ylmethyl)-7H-pyrrolo[2,...)
Affinity DataIC50:  7.10E+4nMAssay Description:IC50 determinations for activated Akt1 were measured with the KinEASE assay (Cisbio) according to the manufacturer’s instructions. The kinases A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed