BDBM153772 US8999981, A17

SMILES COc1cccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2C[C@@H]4CCCN4C[C@@H]2Cc2ccccc2)C3(C)C)c1

InChI Key InChIKey=QPTXUILVOKMXLI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153772   

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 153772BDBM153772(US8999981, A17)
Affinity DataKi:  16.1nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent