BDBM154497 US9012443, 293

SMILES COc1cc(ccc1-c1n[nH]c(=O)c2cc(ccc12)S(=O)(=O)Nc1nccs1)C(F)(F)F

InChI Key InChIKey=LMIJVCDFGCEVCX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 154497   

LigandPNGBDBM154497(US9012443, 293)
Affinity DataIC50:  150nMAssay Description:293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system...More data for this Ligand-Target Pair
In DepthDetails US Patent


LigandPNGBDBM154497(US9012443, 293)
Affinity DataIC50:  150nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM154497(US9012443, 293)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM154497(US9012443, 293)
Affinity DataIC50: >3.00E+4nMAssay Description:293 cells stably transfected with Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system acco...More data for this Ligand-Target Pair
In DepthDetails US Patent