BDBM154592 US8999957, Column 143, Compound 1

SMILES COc1cccc(F)c1CN1CCC[C@@H](NC(=O)c2ccc3[nH]nc(C4=CCOCC4)c3c2)C1

InChI Key InChIKey=ICSYSVGTZHQMRP-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 154592   

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 154592BDBM154592(US8999957, Column 143, Compound 1)
Affinity DataIC50: 1.30nMAssay Description:Condition 2: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2015
Entry Details
US Patent