BDBM15510 (4R,5R)-5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-4-(2,4,5-trifluorophenyl)-piperidin-2-one::(4R,5R)-5-amino-1-[2-(2H-1,3-benzodioxol-5-yl)ethyl]-4-(2,4,5-trifluorophenyl)piperidin-2-one::4, 5-trans -5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-4-(2, 4, 5-trifluorophenyl)piperidin-2-one::Piperidinone-Constrained Phenethylamine 25::Piperidinone-Constrained Phenethylamine 31::Racemic mixture
SMILES N[C@H]1CN(CCc2ccc3OCOc3c2)C(=O)C[C@@H]1c1cc(F)c(F)cc1F
InChI Key InChIKey=DIRIFWIKLRTNMB-DYVFJYSZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 15510
Affinity DataKi: 3.20nM ΔG°: -11.5kcal/molepH: 7.5 T: 22°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of dipeptidyl peptidase 4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 7.10nM ΔG°: -11.0kcal/molepH: 7.5 T: 22°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair