BDBM156399 US9018381, 22::US9248140, 22

SMILES OC[C@H]1CN(CC[C@H](CSc2ccccc2)Nc2ccc(cc2S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c2ccc(cc2)N2CCC(CC2)[C@@H](O)c2ccccc2-c2ccc(Cl)cc2)CCO1

InChI Key InChIKey=UNIDPFJTIWEYGM-UQHKMDGSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 156399   

TargetBcl-2-like protein 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM156399(US9018381, 22 | US9248140, 22)
Affinity DataIC50:  3nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandPNGBDBM156399(US9018381, 22 | US9248140, 22)
Affinity DataIC50:  0.600nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandPNGBDBM156399(US9018381, 22 | US9248140, 22)
Affinity DataIC50:  3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetApoptosis regulator Bcl-2(Human)
Astrazeneca

US Patent
LigandPNGBDBM156399(US9018381, 22 | US9248140, 22)
Affinity DataIC50:  0.600nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent