BDBM156593 US10118915, Compound 371::US20250346584, Compound 248::US9682966, 371

SMILES Cc5ccc4nc(N2CCC(N[C@H]1CCCC[C@@H]1O)CC2)c(c3nc(C)no3)cc4c5

InChI Key InChIKey=VKORYNIHEXANNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156593   

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 156593BDBM156593(US9682966, 371 | US20250346584, Compound 248 | US1...)
Affinity DataIC50: 0.860nMAssay Description:The IC50 of each compound shown in Table was with respect to the kappa opioid receptor was determined. The cell line for the OPRK1 antagonist assay s...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/4/2026
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 156593BDBM156593(US9682966, 371 | US20250346584, Compound 248 | US1...)
Affinity DataIC50: 11nMAssay Description:The IC50 of each compound shown in Table was with respect to the kappa opioid receptor was determined. The cell line for the OPRK1 antagonist assay s...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/4/2026
Entry Details
US Patent