BDBM157441 US9023865, 282

SMILES C[C@@H](NC(=O)Nc1cc2[nH]nc(-c3ccc(=O)[nH]c3)c2cn1)c1ccc(F)cc1

InChI Key InChIKey=MHCSPIWXPQHFEM-ZNCULLJESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 157441   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM157441(US9023865, 282)
Affinity DataIC50:  0.304nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In DepthDetails US Patent