BDBM15786 3-N-{[2-(benzyloxy)-5-(1H-indol-6-yl)phenyl]methyl}pyridine-2,3-diamine::3-Substituted 2-Aminopyridine 8a

SMILES Nc1ncccc1NCc1cc(ccc1OCc1ccccc1)-c1ccc2cc[nH]c2c1

InChI Key InChIKey=IWQIMHIJDLAOHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15786   

TargetBeta-secretase 1(Human)
Astex

LigandPNGBDBM15786(3-N-{[2-(benzyloxy)-5-(1H-indol-6-yl)phenyl]methyl...)
Affinity DataIC50: 690nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed