BDBM15896 4-{6-chloro-9-hydroxy-1-methyl-4-oxo-1H,4H,9H-pyrazolo[3,4-b]quinolin-3-yl}-N-methylbutanamide::9-hydroxy pyrazoloquinolinone 7l

SMILES CNC(=O)CCCc1nn(C)c2n(O)c3ccc(Cl)cc3c(=O)c12

InChI Key InChIKey=RYBVTPJMGWELEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15896   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15896(4-{6-chloro-9-hydroxy-1-methyl-4-oxo-1H,4H,9H-pyra...)
Affinity DataIC50: 750nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2007
Entry Details Article
PubMed