BDBM159369 US9034907, 22

SMILES Cc1cn(CCCn2c(=S)[nH]c3sc4c(c3c2=O)CCC(C)C4)cn1

InChI Key InChIKey=PYQINQYKRFNEDD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159369   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandChemical structure of BindingDB Monomer ID 159369BDBM159369(US9034907, 22)
Affinity DataKi:  430nM ΔG°:  -8.82kcal/mole IC50: 2.32E+3nMpH: 8.0 T: 2°CAssay Description:Fluorometric Assays: All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30 C. QC activity was eval...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent