BDBM159693 US9035059, 14-9

SMILES COc1cc(F)ccc1NS(=O)(=O)c1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=BMKQGGFEZQEHAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159693   

Target2-acylglycerol O-acyltransferase 2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159693(US9035059, 14-9)
Affinity DataIC50: 168nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159693(US9035059, 14-9)
Affinity DataIC50: 168nMAssay Description:Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed