BDBM159897 BDBM159898::US9040528, 53

SMILES C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)-n2cncn2)C(=O)NC(=O)NC1=O

InChI Key InChIKey=XRTAULGTMMIAID-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 159897   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Astrazeneca

US Patent
LigandPNGBDBM159897(BDBM159898 | US9040528, 53)
Affinity DataIC50: 200nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/ml of topologic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
US Patent

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM159897(BDBM159898 | US9040528, 53)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus ATTC 25923 DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Astrazeneca

US Patent
LigandPNGBDBM159897(BDBM159898 | US9040528, 53)
Affinity DataIC50: 2.80E+3nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/ml of topologic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
US Patent

TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM159897(BDBM159898 | US9040528, 53)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed