BDBM160556 US9682980, 3-(Cyclopropylmethyl)-7-(4-(4-fluorophenyl)piperidin-1-yl)-8-methoxy-[1,2,4]triazolo[4,3-c]pyrimidine::US9682980, 3-(Cyclopropylmethyl)-8-methoxy-7-(4-phenylpiperidin-1-yl)-[1,2,4]triazolo[4,3-c]pyrimidine

SMILES COc1c(ncn2c(CC3CC3)nnc12)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=JLPZUFLAKWMESU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 160556   

TargetMetabotropic glutamate receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160556(US9682980, 3-(Cyclopropylmethyl)-7-(4-(4-fluorophe...)
Affinity DataEC50:  519nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160556(US9682980, 3-(Cyclopropylmethyl)-7-(4-(4-fluorophe...)
Affinity DataEC50:  540nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent