BDBM160759 US9682980, 8-Chloro-N-((2-(2-fluoro-6-methoxyphenyl)cyclopropyl)methyl)-3-(2,2,2-trifluoroethyl)-[1,2,4]triazolo[4,3-b]pyridazin-7-amine

SMILES COc1cccc(F)c1C1CC1CNc1cnn2c(CC(F)(F)F)nnc2c1Cl

InChI Key InChIKey=JFHXBFKFLTUNEE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160759   

TargetMetabotropic glutamate receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160759(US9682980, 8-Chloro-N-((2-(2-fluoro-6-methoxypheny...)
Affinity DataEC50:  31nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent