BDBM161590 US9108983, Example 406

SMILES Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2ccccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1

InChI Key InChIKey=NIAFFBFHQJKOPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161590   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM161590(US9108983, Example 406)
Affinity DataIC50: 4.20nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent