BDBM161623 US9108983, Example 440

SMILES COc1cc(C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)c(cc1F)-c1cc(C(=O)N(c2cc(C#N)n(C)c2C)c2ccc(O)cc2)c(C)n1C

InChI Key InChIKey=NQFADRMBOFEGIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161623   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM161623(US9108983, Example 440)
Affinity DataIC50: 2.60nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent