BDBM16171 2-[4-chloro-7-({1-[(4-methylpiperazin-1-yl)carbonyl]cyclopentyl}sulfamoyl)isoquinolin-1-yl]guanidine::cycloleucine deriv. 45

SMILES [#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)C1([#6]-[#6]-[#6]-[#6]1)[#7]S(=O)(=O)c1ccc2c(Cl)cnc(\[#7]=[#6](/[#7])-[#7])c2c1

InChI Key InChIKey=KHAPOCZPLRRWRN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16171   

LigandPNGBDBM16171(2-[4-chloro-7-({1-[(4-methylpiperazin-1-yl)carbony...)
Affinity DataKi:  1.40nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM16171(2-[4-chloro-7-({1-[(4-methylpiperazin-1-yl)carbony...)
Affinity DataKi:  3.47E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasminogen(Human)
Pfizer

LigandPNGBDBM16171(2-[4-chloro-7-({1-[(4-methylpiperazin-1-yl)carbony...)
Affinity DataKi:  6.50E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed