BDBM161915 US10017516, Compound 47::US9682983, 47::US9682983, 49

SMILES C(CN1CCCCC1)Oc1ccc(nc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12

InChI Key InChIKey=YCFHQBMHEXTGMF-UHFFFAOYSA-N

Data  12 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 161915   

TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 94nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Date in BDB:
6/1/2020
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TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 94nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Date in BDB:
3/10/2018
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TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 157nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Date in BDB:
3/10/2018
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TargetSerine/threonine-protein kinase receptor R3(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 257nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Date in BDB:
6/1/2020
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TargetSerine/threonine-protein kinase receptor R3(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 257nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
3/10/2018
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TargetSerine/threonine-protein kinase receptor R3(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 341nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
3/10/2018
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TargetBone morphogenetic protein receptor type-1A(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 1.97E+3nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
6/1/2020
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TargetBone morphogenetic protein receptor type-1A(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 1.97E+3nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair

Target InfoPDB
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Date in BDB:
3/10/2018
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TargetBone morphogenetic protein receptor type-1A(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 3.28E+3nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Date in BDB:
3/10/2018
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TargetBone morphogenetic protein receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 4.08E+3nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
6/1/2020
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TargetBone morphogenetic protein receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 4.08E+3nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
3/10/2018
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TargetBone morphogenetic protein receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent

LigandBDBM161915(US9682983, 47 | US9682983, 49 | US10017516, Compou...)Copy SMILESCopy InChI

Affinity DataIC50: 7.85E+3nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/10/2018
Entry Details
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