BDBM161932 US10017516, Compound 64::US9682983, 64

SMILES Cc1ccc2c(cccc2n1)-c1cnn2cc(cnc12)-c1ccc(O[C@@H]2CCNC2)cn1

InChI Key InChIKey=SQRAKIQIMGAALF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 161932   

TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161932BDBM161932(US9682983, 64 | US10017516, Compound 64)
Affinity DataIC50: 276nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161932BDBM161932(US9682983, 64 | US10017516, Compound 64)
Affinity DataIC50: 276nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161932BDBM161932(US9682983, 64 | US10017516, Compound 64)
Affinity DataIC50: 1.35E+3nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161932BDBM161932(US9682983, 64 | US10017516, Compound 64)
Affinity DataIC50: 1.35E+3nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetBone morphogenetic protein receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161932BDBM161932(US9682983, 64 | US10017516, Compound 64)
Affinity DataIC50: 6.41E+3nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetBone morphogenetic protein receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161932BDBM161932(US9682983, 64 | US10017516, Compound 64)
Affinity DataIC50: 6.41E+3nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetActivin receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161932BDBM161932(US9682983, 64 | US10017516, Compound 64)
Affinity DataIC50: 4.64E+4nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetActivin receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161932BDBM161932(US9682983, 64 | US10017516, Compound 64)
Affinity DataIC50: 4.64E+4nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent