BDBM161935 US10017516, Compound 67::US9682983, 67

SMILES COc1ccc2c(cccc2n1)-c1cnn2cc(cnc12)-c1ccc(cc1)N1[C@@H](C)CNC[C@H]1C

InChI Key InChIKey=URUAVMYQAQXGRF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 161935   

TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161935BDBM161935(US9682983, 67 | US10017516, Compound 67)
Affinity DataIC50: 157nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetActivin receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161935BDBM161935(US9682983, 67 | US10017516, Compound 67)
Affinity DataIC50: 157nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161935BDBM161935(US9682983, 67 | US10017516, Compound 67)
Affinity DataIC50: 618nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161935BDBM161935(US9682983, 67 | US10017516, Compound 67)
Affinity DataIC50: 618nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetActivin receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161935BDBM161935(US9682983, 67 | US10017516, Compound 67)
Affinity DataIC50: 2.26E+4nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetActivin receptor type-1B(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161935BDBM161935(US9682983, 67 | US10017516, Compound 67)
Affinity DataIC50: 2.26E+4nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161935BDBM161935(US9682983, 67 | US10017516, Compound 67)
Affinity DataIC50: 5.36E+4nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2-6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
The Brigham and Women'S Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 161935BDBM161935(US9682983, 67 | US10017516, Compound 67)
Affinity DataIC50: 5.36E+4nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE Ultra ULight technology (Perkin Elmer) against h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent