BDBM162124 US9682995, 36

SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2ncccc2C#N)cn1

InChI Key InChIKey=CJTRBMPQEWPGAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162124   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 162124BDBM162124(US9682995, 36)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:N-terminally His6-tagged recombinant catalytic domain of human Bub1 (amino acids 704-1085), expressed in insect cells (Hi5) and purified by Ni-NTA af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 162124BDBM162124(US9682995, 36)
Affinity DataIC50: 2.00E+4nMpH: 7.7 T: 2°CAssay Description:N-terminally GST-tagged human full length recombinant Mps-1 kinase (purchased from Invitrogen, Karslruhe, Germany, cat. no PV4071) was used. As subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent