BDBM162323 US10307427, Compound 14::US9051313, 14

SMILES C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(c(cn2)N2CCC(C)(O)CC2)-n2cnc(c2)C2CC2)cs1)C(F)(F)F

InChI Key InChIKey=MQGKAHLKCUKYGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162323   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gildead Sciences

US Patent
LigandPNGBDBM162323(US9051313, 14 | US10307427, Compound 14)
Affinity DataIC50: 1.80nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gildead Sciences

US Patent
LigandPNGBDBM162323(US9051313, 14 | US10307427, Compound 14)
Affinity DataIC50: 1.80nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent