BDBM162852 US9056843, 143

SMILES CCCN(C)C[C@@H](C)NC(=O)c1ccc(cc1F)-c1noc(n1)C(F)(F)F

InChI Key InChIKey=OBJZEJYAHAWEPJ-SNVBAGLBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 162852   

TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM162852(US9056843, 143)
Affinity DataIC50:  5.80E+3nMpH: 8.0 T: 2°CAssay Description:A similar assay procedure as described in Test 2 was used for HDAC1. Human recombinant full length HDAC1 expressed in a baculovirus expression system...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM162852(US9056843, 143)
Affinity DataIC50:  3.30E+3nMpH: 8.0 T: 2°CAssay Description:A similar assay procedure as described in Test 2 was used for HDAC6. Human recombinant full length HDAC6 expressed in a baculovirus expression system...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM162852(US9056843, 143)
Affinity DataIC50:  1.20nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In DepthDetails US Patent