BDBM163055 US9062004, 20::US9670216, 20 2-(3,5-Bistrifluoromethylphenyl)-4-chloro-5-propylaminopyridazin-3-one

SMILES CCCNc1cnn(-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(=O)c1Cl

InChI Key InChIKey=LKHROGMZUBZXNT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 163055   

TargetCannabinoid receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM163055(US9062004, 20 | US9670216, 20 2-(3,5-Bistrifluorom...)
Affinity DataIC50: 1.00E+4nMAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 .mu.mol/mg protein, receptor co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM163055(US9062004, 20 | US9670216, 20 2-(3,5-Bistrifluorom...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 pmol/mg protein, receptor conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Allergan

US Patent
LigandPNGBDBM163055(US9062004, 20 | US9670216, 20 2-(3,5-Bistrifluorom...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 pmol/mg protein, receptor conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Allergan

US Patent
LigandPNGBDBM163055(US9062004, 20 | US9670216, 20 2-(3,5-Bistrifluorom...)
Affinity DataIC50: 1.00E+4nMAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 .mu.mol/mg protein, receptor co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
US Patent