BDBM163363 US9687479, 259 ethyl 2-[3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1-[(furan-3-yl)carbonyl]-1H-pyrazol-3-yl)-2-oxo-1,2-dihydropyridin-1-yl]acetate

SMILES CCOC(=O)Cn1cccc(-c2cc(NCc3ccc(Cl)s3)n(n2)C(=O)c2ccoc2)c1=O

InChI Key InChIKey=JENOFIWACADOMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163363   

TargetProthrombin(Human)
Verseon

US Patent
LigandPNGBDBM163363(US9687479, 259 ethyl 2-[3-(5-[(5-chlorothiophen-2-...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Human thrombin was obtained from Haematologic Technologies Inc. The chromogenic substrate S-2238 was obtained from DiaPharma. Thrombin was assayed in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent