BDBM163599 US9687479, 364 3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1-[(2-methoxyphenyl)carbonyl]-1H-1,2,4-triazol-3-yl)-N,N-dimethylazetidine-1-sulfonamide

SMILES COc1ccccc1C(=O)n1nc(nc1NCc1ccc(Cl)s1)C1CN(C1)S(=O)(=O)N(C)C

InChI Key InChIKey=WJVWYNJXYHRVTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163599   

TargetPlasma kallikrein(Human)
Verseon

US Patent
LigandPNGBDBM163599(US9687479, 364 3-(5-[(5-chlorothiophen-2-yl)methyl...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Human KLKB1 protein was obtained from Enzyme Research Labs. The chromogenic substrate S-2302 was obtained from DiaPharma. KLKB1 was assayed in buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent