BDBM164970 US9067917, 1::US9067917, 21::US9682971, 21

SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1

InChI Key InChIKey=SBLFULGYUXMXLD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 164970   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM164970(US9067917, 1 | US9067917, 21 | US9682971, 21)
Affinity DataKi:  3.60nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM164970(US9067917, 1 | US9067917, 21 | US9682971, 21)
Affinity DataKi:  3.60nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM164970(US9067917, 1 | US9067917, 21 | US9682971, 21)
Affinity DataKi:  7.80nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM164970(US9067917, 1 | US9067917, 21 | US9682971, 21)
Affinity DataKi:  7.80nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent