BDBM16521 2-arylpyridazin-3-one, 27::6-[(2-chloro-4-fluorophenyl)(2-hydroxyethyl)amino]-2-(2-chlorophenyl)-2,3-dihydropyridazin-3-one

SMILES OCCN(c1ccc(=O)n(n1)-c1ccccc1Cl)c1ccc(F)cc1Cl

InChI Key InChIKey=SSVPNEAXULRSCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16521   

TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

LigandPNGBDBM16521(2-arylpyridazin-3-one, 27 | 6-[(2-chloro-4-fluorop...)
Affinity DataIC50:  135nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandPNGBDBM16521(2-arylpyridazin-3-one, 27 | 6-[(2-chloro-4-fluorop...)
Affinity DataIC50:  168nMpH: 7.0 T: 30°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed