BDBM16523 2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-trimethoxyphenyl)methyl]amino}propyl)amino]-2,3-dihydropyridazin-3-one::2-arylpyridazin-3-one, 29

SMILES COc1ccc(CNCCCN(c2ccc(=O)n(n2)-c2ccccc2Cl)c2ccccc2Cl)c(OC)c1OC

InChI Key InChIKey=OLFNUOKBBIASKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16523   

TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16523(2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-...)
Affinity DataIC50:  600nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16523(2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-...)
Affinity DataIC50:  490nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed