BDBM167180 US9073876, 261::US9732093, Compound 261

SMILES CC(C)CNc1nccc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)n1

InChI Key InChIKey=SQWYWDWUIBZONM-UHFFFAOYSA-N

Data  3 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 167180   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent

LigandBDBM167180(US9073876, 261 | US9732093, Compound 261)Copy SMILESCopy InChI

Affinity DataKi:  1.30nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent

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TargetFlap endonuclease 1(Human)
Janssen Pharmaceutica

US Patent

LigandBDBM167180(US9073876, 261 | US9732093, Compound 261)Copy SMILESCopy InChI

Affinity DataKi:  1.30nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent

Copy BDB DOI
Copy reaction URL

TargetFlap endonuclease 1(Human)
Janssen Pharmaceutica

US Patent

LigandBDBM167180(US9073876, 261 | US9732093, Compound 261)Copy SMILESCopy InChI

Affinity DataKi:  2.20nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent

Copy BDB DOI
Copy reaction URL