BDBM167388 US9073881, 140

SMILES Cc1ccc(Cl)c(-c2ccc(-c3nc(-c4ccc(Cl)c(Cl)c4)cs3)cc2C(=O)O)c1F

InChI Key InChIKey=ZNMDDOAYHHCMLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167388   

TargetEukaryotic translation initiation factor 4E(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 167388BDBM167388(US9073881, 140)
Affinity DataIC50: 700nMpH: 7.0Assay Description:Human eIF4E (aa 28-217) with a C-terminal His tag (HH-eIF4E) was expressed in E. coli in inclusion bodies. The protein was solubilized with 8 M urea ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent