BDBM167430 US9073893, 63
SMILES Cn1n(C2CCN(Cc3cccs3)CC2)c(=O)c2c(cccc12)C(N)=O
InChI Key InChIKey=TVMQVMPQEYUIGQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 167430
Affinity DataIC50: 130nMT: 37°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
Affinity DataKd: <10nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair