BDBM168082 US9073931, E8b::US9073931, E8c

SMILES CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F

InChI Key InChIKey=WAZXSGZGKNWHSO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 168082   

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM168082(US9073931, E8c | US9073931, E8b)
Affinity DataKi:  9nM ΔG°:  -11.0kcal/moleT: 2°CAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
US Patent

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM168082(US9073931, E8c | US9073931, E8b)
Affinity DataKi:  13nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM168082(US9073931, E8c | US9073931, E8b)
Affinity DataKi:  65nM ΔG°:  -9.80kcal/moleT: 2°CAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM168082(US9073931, E8c | US9073931, E8b)
Affinity DataKi:  74nM ΔG°:  -9.72kcal/moleT: 2°CAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
US Patent